A Pharmacokinetic Simulation Tool for Inhaled Corticosteroids
نویسندگان
چکیده
منابع مشابه
Inhaled Corticosteroids
Inhaled corticosteroids (ICS) are the most effective controllers of asthma. They suppress inflammation mainly by switching off multiple activated inflammatory genes through reversing histone acetylation via the recruitment of histone deacetylase 2 (HDAC2). Through suppression of airway inflammation ICS reduce airway hyperresponsiveness and control asthma symptoms. ICS are now first-line therapy...
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ژورنال
عنوان ژورنال: The AAPS Journal
سال: 2012
ISSN: 1550-7416
DOI: 10.1208/s12248-012-9420-z